COMPARATIVE PHYTOCHEMICAL PROFILING AND SPECTROSCOPIC CHARACTERISATION OF ELAEOCARPUS GANITRUS AND WITHANIA SOMNIFERA EXTRACTS: IMPLICATIONS FOR EPILEPSY MANAGEMENT
DOI:
https://doi.org/10.65327/ans.v11i1.2477Keywords:
Elaeocarpus ganitrus, Withania somnifera, Phytochemical screening, GC–MS analysis, FTIR spectroscopyAbstract
Medicinal plants are important sources of bioactive compounds with potential therapeutic applications. The present study aimed to perform a comparative phytochemical characterisation and GC–MS profiling of ethanolic extracts of Elaeocarpus ganitrus and Withania somnifera. Preliminary phytochemical screening revealed the presence of major phytoconstituents such as flavonoids, tannins, polyphenols, glycosides, and alkaloids in both extracts. UV–Visible spectroscopic analysis showed characteristic absorption peaks around 200–210 nm and 250–280 nm, indicating the presence of conjugated aromatic compounds and phenolic constituents. FTIR spectral analysis confirmed the presence of functional groups, including hydroxyl, carbonyl, and aromatic C=C bonds, suggesting the occurrence of phenolic and oxygenated phytochemicals. GC–MS analysis further identified several bioactive compounds, including phenolic derivatives and aromatic constituents, in both plant extracts. These phytochemicals are recognised for their antioxidant and neuroprotective properties, which may contribute to their potential pharmacological activity. Comparative analysis revealed overlapping classes of bioactive constituents in both plants, highlighting their significance as sources of biologically active molecules. The findings provide a scientific basis for further pharmacological investigations of these plants and support their traditional medicinal use.
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